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Cannabidiol has low affinity for the cannabinoid CB 1 and CB 2 receptors, although it can act as an antagonist of CB 1 /CB 2 agonists despite this low affinity. Cannabidiol may be an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain.

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CBD hemp oil is derived from cannabis plants, excluding there is some difference between them, which makes ingredient as mentioned earlier non-psychoactive. Cannabidiol is squeezed from flowers, on the contrary, hemp ones are produced from the seeds. Not similar to medical marijuana, cannabidiol has a low concentration of THC (close to 0.28%

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